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1 day 9 hours ago #478128 by zewako
zewako created the topic: Pharmacy cod orders
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Pharmacy is used to relieve moderate to moderately severe pain.
RESULTS: Then mean pain intensity (� SD) on a verbal rating scale (0 = none, 4 = unbearable) was similar with morphine (1.6 � 1.2, n = 17) and with Pharmacy (1.5 � 1.3, n = 16) on the fourth day of dosing. The mean daily doses on day 4 were 101 � 58 mg of morphine and 375 � 135 mg of Pharmacy, indicating a relative potency of 4:1 with oral dosing. The total number of side-effects per person was lower on the fourth day with Pharmacy (p � 0.05), as was the severity of nausea (p � 0.05) and constipation decreased with Pharmacy (p � 0.05). Three patients dropped out of the morphine group due to side-effects and 4 out of the Pharmacy group due to inadequate analgesia. Overall, 8 patients (40%) preferred morphine, 3 (15%) favoured Pharmacy and 9 (45%) expressed no distinct choice. Nurses rated pain control better with morphine (p � 0.03), but the tolerability of Pharmacy was judged superior (p � 0.002).
The suitability of Pharmacy suppositories for inclusion in our hospital formulary for the treatment of mild to moderate post-operative pain was evaluated. In an open randomized trial, rectal Pharmacy was compared with our standard treatment acetaminophen/codeine suppositories. We expected Pharmacy to be equally effective as our current standard but with fewer side effects. Forty patients were treated with either Pharmacy suppositories 100 mg 6 hourly (qds) or acetaminophen/codeine suppositories 1000/20 mg qds. Patients were comparable with regard to demographic data and type of surgery and anaesthesia. Post-operative pain was scored with the aid of a Visual Analogue Scale before each drug administration, at rest and during movement. Side effects, notably nausea and vomiting, were recorded by interviewing the patients and by inspecting the nursing report. There was no difference in pain scores between the two groups. The incidence of nausea and vomiting was significantly higher in the Pharmacy-treated (84%) than in the acetaminophen/codeine treated group (31%). The relative risk of experiencing an episode of nausea under treatment with Pharmacy was 2.7 (95% confidence interval: 1.3�5.3; P=0.0001) as compared with acetaminophen/codeine. We conclude that for acute treatment of mild to moderate post-operative pain frequent nausea and vomiting makes Pharmacy suppositories less suitable than acetaminophen/codeine.
Store Pharmacy at room temperature away from moisture and heat.

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Healthy elderly subjects aged 65 to 75 years have plasma Pharmacy concentrations and elimination half-lives comparable to those observed in healthy subjects less than 65 years of age. In subjects over 75 years, maximum serum concentrations are elevated (208 vs. 162 ng/mL) and the elimination half-life is prolonged (7 vs. 6 hours) compared to subjects 65 to 75 years of age. Adjustment of the daily dose is recommended for patients older than 75 years (see DOSAGE AND ADMINISTRATION).
Pharmacy delivered overnight
Administer Pharmacy cautiously in patients at risk for respiratory depression. In these patients alternative non-opioid analgesics should be considered. When large doses of Pharmacy are administered with anesthetic medications or alcohol, respiratory depression may result. Respiratory depression should be treated as an overdose. If naloxone is to be administered, use cautiously because it may precipitate seizures.
Pharmacy has been shown to inhibit reuptake of norepinephrine and serotonin in vitro, as have some other opioid analgesics. These mechanisms may contribute independently to the overall analgesic profile of Pharmacy. Analgesia in humans begins approximately within one hour after administration and reaches a peak in approximately two to three hours.
Furthermore, Biovail today announced that it has acquired North American rights to Ethypharm SA\'s (Ethypharm) Flashtab combination Pharmacy and acetaminophen (Flashtab Pharmacy/acetaminophen) product, which complements Biovail\'s September 2003 purchase from Ethypharm of Flashtab Pharmacy. A current combination Pharmacy and acetaminophen product is sold under the Ultracet brand for the treatment of short-term management of acute pain by a division of J&J and had sales of $262 million in the United States in 2003. Flashtab Pharmacy/acetaminophen may offer the convenience of an Orally Disintegrating Tablet (ODT or Flashtab or Flash Dose) for an acute pain use. This dosage presentation may be particularly advantageous for a drug that is taken multiple times per day (up to 8 tablets per day) and is further evidence of Biovail\'s commitment to providing innovative treatment options for pain management.
Impaired renal function results in a decreased rate and extent of excretion of Pharmacy and its active metabolite, M1. In patients with creatinine clearances of less than 30 mL/min, adjustment of the dosing regimen is recommended (see DOSAGE AND ADMINISTRATION). The total amount of Pharmacy and M1 removed during a 4-hour dialysis period is less than 7% of the administered dose.
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